DNA sequencing to meet global biodiversity goals: Interview with Tyler Kartzinel Tyler sat down for an interview with Abhishyant Kidangoor of Mongabay to discuss our recent Mini Review in Molecular Ecology, entitled Global Availability of Plant DNA Barcodes as Genomic Resources to Support Basic and Policy-Relevant Biodiversity Research.
You can read our conversation here at Mongabay. It covers topics that are among the most important for ensuring the reliability of DNA-based biodiversity research, including equitable access to the benefits arising from this technology and the reputations of all who use it. Here are the points that Mongabay highlighted from our interview:
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One of the top “unsolved problems” in biology is the need to untangle complex networks of species interactions - perhaps nowhere is this more consequential than our need to grapple with the socioecological risks of neglected tropical diseases. Human-livestock-wildlife parasite transmission has been declared a major biomedical challenge for the 21st century with reasons for concern that include the potential for zoonotic helminths—parasitic worms such as nematodes (roundworms), cestodes (tapeworms), and trematodes (flukes) to be transmitted between humans and animals. The effects cause malnutrition, developmental delays, and deaths that disproportionately affect communities undergoing rapid development.
A critical problem is that our strategies to identify and track wildlife parasites originated to combat livestock diseases a century ago. We know very little about how to answer the question: What parasites infect tropical wildlife? We know far more about the subset of parasites that harm humans and livestock than all others. Consequently, our conservation partners struggle to identify the parasites they encounter, hindering our collective efforts to rehabilitate endangered species, evaluate emerging health threats, and treat diseases. Fortunately, we have just received a Catalyst award from the Institute at Brown for Environment and Society to pursue new strategies. Today, the gold-standard method for studying gastrointestinal helminth parasites in wildlife is rooted in taxonomy. Identifying parasites and evaluating their potential to harm hosts requires us to inspect adult parasites from dead hosts. Of course dead-but-well-preserved wildlife are hard to find, especially in the tropics. As a result, we often rely on less-suitable counts of parasite eggs in fecal samples, which can reveal parasites are present but often precludes identification or comparison across studies. This award will allow us to build on recent work at Brown University, which has brought us tantalizingly close to sparking a new era of genome-enabled parasitology that could overcome these intersecting challenges. Together with an exciting array of partners - Sloth Conservation Foundation (Costa Rica), The Organization for Tropical Studies (Costa Rica), Fundación Zoológica de Cali (Colombia), and the Instituto de Biología Subtropical (Argentina) - we are embarking on an ambitious plan to document and DNA barcode parasites from tropical wildlife across the Americas. We are also expanding our work at Brown, tapping into the expertise of tapping into the GeoSpatial expertise of Professor of the Practice Seda Şalap-Ayça and Data Scientist Tim Divoll to build more user-friendly and informative data portals. We are grateful for the new support to build and share this important resource! |
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